Since I am one-eighth Cherokee and my spouse is the daughter of immigrants from Italy, our marriage was interracial and presumably illegal in Virginia. We often entertained renting a hotel room in Virginia as a sexy way to protest the Virginia law. We never did. It was cheaper to go home to the District of Columbia and make love there. In our case, economics trumped making a political statement.
In 1967 the Supreme court ruled in the case of Loving & Loving versus the State of Virginia, that the 1924 ban on interracial marriage was unconstitutional. I do not remember that the ban interfered with medical, inheritance or other important decisions in Virginia. The main effect was the promotion of a slightly naughty amusement on the part of couples like us.
The lesson for the same-sex marriage cases now before the Supreme Court seems to me to be the current cases are not very important in terms of changing behavior. Nevertheless, public opinion is still sharply divided.
This suggests that a decision from the United States Supreme Court may be premature. There is a dictum from the legal literature that is on point in my opinion: Hard decisions make bad law.